Peyronies disease - causes, symptoms, and treatment

Medically Reviewed by Dr Sravya, MBBS, MS 

Peyronies disease - An overview

Peyronies disease is a skin disorder caused by scaring of tissues beneath the skin of the penis – the male sexual organ.

peyronies disease

It is majorly due to the plaque formation in the layers of Tunica Albuginea, causing curvature of the penis. This curvature could range from slight to severe, leading to painful erections.

Table of Contents

How common is the occurrence?

According to the research, though its occurrence is rare in young men, it is estimated that about 4 in 100 men in the age group of 40-70 years are highly prone to Peyronies.

What causes Peyronies ?

Peyronie’s is caused by various factors, such as

Risk factors that can cause Peyronies

Autoimmune diseases associated with Peyronies are :

Other risk factors include :

Symptoms associated with Peyronie’s

The most important and primary symptom to note in Peyronies is the curved penis. This curvature could be either upwards, downwards, or to the side. The second most important to note is the scars that cause the Peyronies. These scars may present as

The third and foremost symptom is Ed (erectile dysfunction)

 The other symptoms include –

These symptoms may vary from mild to severe forms, and they can either present themselves slowly or quickly.

Stages of Peyronies

Peyronies is split into two stages

1. Acute Phase: Acute phase usually lasts for about 5-7 months and, at times, may last for 18 months. This is the phase where in-

2. Chronic Phase: Chronicphase begins with the formation of plaques or when y the plague is completed. This begins around 12-18 months after the first symptom appears. In this phase-

How are the Peyronies diagnosed?

Diagnosis of Peyronies is done by the following methods:

1. Physical examination: the doctor usually conducts a physical exam through which he identifies the lumps or the plaques that can easily be felt over the penis. Besides, the physician may inject a drug to test for the curvature of your penis.

2. Ultrasound: this is done to identify additional information regarding plaque or
check for any calcifications besides identifying the exact location of the plaque

3. Urologist: Mostly, men with peyronies are referred to a urologist for
examination who further cross-checks their family history, which includes
gathering information about –

Treatment and management of Peyronies

Usually, Peyronies is a self-remitting disease that goes away with time. In a few cases where intervention is sought, treatment modalities are suggested based on the needs and requirements of an individual.

The treatment modalities include –

1.Non-surgical treatment: This includes injections, oral medicines, and medical therapies

Collagen Intralesional injection helps break down the collagen that helps the formation of plaques, which in turn reduces penile curvature and erections.

These shots may be given over 3 months duration, depending on severity.

2.Oral medicines

While there are no oral medications to treat Peyronies, there are prescribed and over-the-counter drugs that can help deal with symptoms and pain relief and curb other factors that cause it. These include-

3.Non-medical therapy:

These are not much into practice or rather being studied. These include-

Surgical modalities

Surgical correction or treatment is recommended in those men who,

What are the implicated complications?

Advice given for Post-surgical care

There are a few tips and care advised post surgery which include,


Peyronies disease affects men not just physically but also at psychological levels as it impacts the bond and the sex life you have with your partner. Most men shy away from discussing the problem and suffer in silence. It is best advised to open up to your doctor or your close family member, who can help you find the right solution to your problem.

Frequently Asked Questions

In most cases, Peyronies is self-remitting. It goes away on its own. The
shortening and the scars are permanent

No Peyronies does not turn cancerous.Even the cells that cause
plague are benign.

In some cases, men with Peyronies tend to show fibrosis in their
hands and feet.

Since there is no evidence of what causes peyronies, it can be prevented.

Viagara directly does not impact or cause Peyronies but it said to alleviate ED and penis curvature in men who are in the early stage of Peyronies.